Day

Every month on Monday or Tuesday

Time

5.30 p.m. - 6.30 p.m. Presentations and discussion

6.30 p.m. - 7.00 p.m. Pizza and drinks

Venue

MAASTRO-Clinic, Dr. Tanslaan 12, Refereerruimte, level 3

• Department of Pathology - Prof.dr. A. Griffioen
  "Targeting angiogenesis for the treatment of cancer"
• Department of Genetics & Cell Biology (Clinical Genetics) - Drs. J. Bakker
  "Mercaptopurine metabolism revisited"

• Tuesday February 3, 2009

• Department of Obstetrics and Gynaecology - B. Delvoux & Dr. A. Romano
  "Increased production of 17beta-estradiol in endometriosis lesions is the result of impaired metabolism"
• Department of Pathology - S. Derks, MD
  "Epigenetic inactivation targets the Deleted in Colon Cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21"
• Department of Paediatrics - Dr. F. van Iwaarden
  "Interaction of surfactant protein A (SP-A) with TGF-b1"

• Monday March 2, 2009

• Department of Genetics and Cell Biology (Molecular Genetics) - P. Prickaerts, Msc
  "Chromatin out of breath - the interdependency of hypoxic signaling and Polycomb function"
• Department of Dermatology - Drs. T. Claessens
  "The Birt-Hogg-Dubé syndrome: Folliculin dependent regulation of HIF-2alpha"
• Department of Epidemiology - A. Voogd, PhD
  "Studies on determinants of loco-regional tumour relapse in patients with breast cancer"

• Tuesday April 7, 2009

• Department of Internal Medicine - S. Cloosen, PhD
  "Immune reconstitution after donor stem cell transplantation"
• Department of Genetics & Cell Biology (Clinical Genomics) -  B. van den Bosch, PhD
  "New genes and pathophysiological mechanisms in mitochondrial disorders"
• Department of Genetics and Cell Biology (Molecular Cell Biology) - D. Swarts, Msc
  "Genetic analysis of typical and atypical lung carcinoids by ArrayCGH"

• Monday May 11, 2009

• Department of Obstetrics and Gynaecology - J. Spaan, MD
  "Reduced renal function in middle-aged women with a history of preeclampsia at least 20 years earlier”
• Department of Internal Medicine (Medical Oncology) - M. de Boer, MD
  "Micrometastases and Isolated tumor cells: Relevant and Robust or Rubbish? The MIRROR study”
• Department of Epidemiology - Drs. J. Hogervorst
  "Dietary acrylamide intake and human cancer risk"

• Tuesday June 2, 2009

• MAASTRO Lab - B. Jutten, Bsc
  "The EGFR deletion mutant vIII in malignant human tumors- influence on
  tumor microenvironment and treatment response"
• Department of Obstetrics and Gynaecology - A. van Montfoort, PhD
  "X-Choromosome inactivation in human embryos"
• Department of Genetics and Cell Biology (Clinical Genomics) - T. Ayoubi, PhD
  "The molecular in silico dissection of disease and its application in personalized medicine"

• Tuesday September 1, 2009

• Department of Health, Ethics and Society - Prof. dr. G. de Wert
  "Oocyte cryopreservation for non-medical reasons: Ethical reflection"
• Department of Otorhinolaryngology - Head and Neck Surgery / Dept. of Molecular Cell Biology - R. Hamers, MSc
  "Chromosome instability predicts the progression of oral premalignant lesions"
• MAASTRO Clinic - Drs. M. Kimman
  "Follow-up after treatment of breast cancer: Is there a role for patient preferences? - An investigation of patient preference heterogeneity using a discrete choice experiment"

• Monday October 5, 2009

• Poly clinic Clinical Genetics - Drs. M. Vreeburg
  "A multidisciplinary approach to genodermatology: an overview of five years of collaboration"
• Department of Otorhinolaryngology - Head & Neck Surgery / Dept. of Molecular Cell Biology - N. Olthof, MSc
  "Analysis of HPV-integration and the expression of cell cycle and intermediate filament proteins in HPV-positive HNSCC cell lines"
• Department of Obstetrics and Gynecology - A. van Dongen, MD
  "Reasons for dropping out from a waiting list for in vitro fertilization"

• Tuesday November 3, 2009

• Department of Orthopaedic Surgery - M. Caron, MSc
  "Chondrogenesis of mesenchymal progenitors is determined by an early inflammatory response and NF-kB activation"
• Department of Radiology / Surgery - D. Lambregts, MD & M. Maas, MD
  "New MR imaging strategies to optimize treatment planning in rectal cancer"
• Department of Genetics and Cell Biology (Molecular Cell Biology) - Dr. A. Hopman
  "HPV genomic integration or genomic instability as driver for uterine cervical (pre)neoplasia"

• Monday December 7, 2009

• Department of Paediatrics - Dr. E. Villamor
  "Vascular oxygen sensing and signaling: old and new mediators"
• Department of Obstetrics and Gynaecology - Dr. A. Romano
  "Estrogen and EGF signalling control Olfactomedin-4 expression in the human endometrium"
• Department of Clinical Genetics - Dr. S. Frints
  "Histone Modifications and X-inactivation in preimplantation mammalian embryo: A pilot study"

Below you can find the schedule for the pizza meetings of 2010, the appropriate speakers and the titles of their talks will be available in due time:

• Tuesday January 5, 2010 

• MAASTRO Clinic - Merel Kimman, MSc
  "Improving the efficiency and quality of follow-up in the first 18 months after curative treatment for breast cancer"
• Department of Pathology - Jürgen Veeck, PhD
  "Breast Cancer Epigenetics – Biology and Biomarkers"
• Department of Pediatrics / Neonatology - Dr. Danilo Galivanes
  "Antenatal CNS inflammation - More than brain white matter injury"

• Tuesday February 2, 2010

• Department of Obstetrics and Gynecology - Dr. Toon van Gorp
  "Ovarian cancer biomarker discovery"
• Department of Molecular Cell Biology- Jos Broers, PhD
  "Nuclear explosions: compromised nuclear integrity and cytoskeletal functioning in laminopathies"
• Department of Pathology - Ingrid Bijsmans, MSc
  "Betaine-homocysteine methyltransferase 2 (BHMT2) is a candidate tumor suppressor gene frequently inactivated by promoter CpG island hypermethylation in serous ovarian cancer"

Monday March 1, 2010

• Department of Epidemiology - Jessie Steevens, MSc
  "Risk factors for Barrett’s esophagus and subtypes of esophageal and gastric cancer"
• Dept. of Genetics & Cell Biology – Molecular Genetics - Drs. Guus van den Akker
  "Immediate early responses last a long time"
• Deparment of Dermatology - Dr. Jorge Frank
  "Genetic and cell biologic analysis of novel fumarate hydratase missense mutations associated with HLRCC"