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This mission statement originates from the strong parallelisms between the processes of normal and abnormal growth. Tissue growth is mainly the result of a balance between cell proliferation and cell loss. These processes are key features of normal (embryologic) development as well as abnormal (oncologic) growth. As a consequence research lines in early human development and oncology are closely interrelated in their basic concepts as well as in the application of research techniques. Processes like apoptosis, angiogenesis, cellular oxygen supply and genetic programming are all key features in normal and abnormal growth. Due to the strong developments in molecular biology, leading to new science areas and corresponding new techniques like genomics and proteomics, growth can be further analysed and defined on a molecular basis. Since growth (normal and abnormal) is extremely important in medicine, the possibilities to influence normal and abnormal growth are of utmost clinical relevance.
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