Another important output parameter is the number of PhD theses produced by the researchers within GROW. A distinct increase in the number of PhD theses per year can be observed:

Number of PhD theses over the period 2000 – 2009

Overview UM-defended GROW PhD theses

2009

M.H.J. van den Beuken-van Everdingen (2009, January 15^th)

Symptoms in Patients with Cancer

Promotors: prof.dr. M. van Kleef, prof.dr. H.C. Schouten

Co-promotors: dr. J. Patijn, dr. J.M. de Rijke

H.C. Hafkamp (2009, February 6^th)

The role of human papillomavirus in the Development of tonsillar squamous cell carcinomas

Promotors: prof.dr. J.J. Manni, prof.dr. F.C.S. Ramaekers

Co-promotor: dr. E.J.M. Speel

W.J.C. van Elmpt (2009, March 19^th)

3D dose verification for advanced radiotherapy

Promotor: prof.dr. P. Lambin

Co-promotors: dr. A.L.A.J. Dekker, dr. B.J. Mijnheer

R.C. Dresen (2009, March 27^th)

Multidisciplinary approach to locally advanced and recurrent rectal cancer

Promotors: prof.dr. R.G.H. Beets-Tan, prof.dr. J.E. Wildberger

Co-promotors: dr. H.J.T. Rutten, dr. G.L. Beets

M.J. Lahaye (2009, March 27^th)

MRI in Rectal Cancer; prediction of the risk factors for a local recurrence

Promotors: prof.dr. R.G.H. Beets-Tan, prof.dr. J.M.A. van Engelshoven

Co-promotor: dr. G.L. Beets

S.M.F. Engelen (2009, March 27^th)

MRI-based Tailored Treatment of Rectal Cancer: impact on surgical outcome

Promotors: prof.dr. R.G.H. Beets-Tan, prof.dr. C.J.H. van de Velde, prof.dr. M.F. von Meyenfeldt

Co-promotor: dr. G.L. Beets

A. Woldemichael Mengesha (2009, April 1^st)

Use of non-pathogenic bacteria as vectors for targeted gene expression in cancer gene therapy

Promotor: prof.dr. P. Lambin

Co-promotor: dr. J. Theys

S.M.J.J.G. Nijsten (2009, May 20^th)

Portal Dosimetry in Radiotherapy

Promotor: prof.dr. P. Lambin

Co-promotors: dr. A.L.A.J. Dekker, dr. A.W. Minken, dr. B.J. Mijnheer

S.C. de Vogel (2009, June 18^th)

Dietary folate, genetic variation and DNA methylation in sporadic colorectal cancer

Promotor: prof.dr. P.A. van den Brandt

Co-promotors: dr. M. van Engeland, dr. M.P. Weijenberg

M.M.L.L. Baldewijns (2009, June 26^th)

Genetics, Epigenetics and Angiogenesis in Renal Cell Carcinoma

Promotor: prof.dr. A.P. de Bruïne

Co-promotors: dr. A.H.M. Vermeulen, dr. M. van Engeland

R.J. Damstra (2009, June 26^th)

Diagnostic and therapeutical aspects of lymphedema

Promotor: prof.dr. P.M. Steijlen

Co-promotors: dr. M.A.M. van Steensel, dr. J.C.J.M. Veraart

E.M. Heuts (2009, July 2^nd)

Axillary and internal mammary sentinel node biopsy in breast cancer

Promotor: prof.dr. M.F. von Meyenfeldt

Co-promtors: dr. F.W.C. van der Ent, dr. A.C. Voogd

C.E.H. Dirix (2009, July 3^rd)

The functionality of maternal and neonatal fatty acids

Promotors: prof.dr. G. Hornstra, prof.dr. J.G. Nijhuis

S. Derks (2009, October 2^nd)

The interplay between genetics and epigenetics in colorectal cancer

Promotors: prof.dr. A.P. de Bruïne, prof.dr. G.A. Meijer

Co-promotor: dr. M. van Engeland

J.G.F. Hogervorst (2009, October 2^nd)

Dietary acrylamide intake and human cancer risk

Promotor: prof.dr. P.A. van den Brandt

Co-promotors: dr. L.J. Schouten, dr. E.J.M. Konings

E.J. Bloemen-van Gorp (2009, October 30^th)

In vivo dosimetry using MOSFET detectors in radiotherapy

Promotor: prof.dr. P. Lambin

Co-promotors: dr. A.L.A.J. Dekker, dr. B.J. Mijnheer

F.J.H.M. van den Biggelaar (2009, November 6^th)

New approaches to improve the evaluation of mammograms

Promotor: prof.dr. J.M.A. van Engelshoven

Co-promotor: dr. K. Flobbe

J.M.C. Maessen (2009, November 6^th)

Enhanced Recovery After Surgery Fact or Fiction?

Promotors: prof.dr. M.F. von Meyenfeldt, prof.dr. C.H.C. Dejong

H.E.C. Niessen (2009, November 13^th)

Regulation of Polycomb Group proteins. The complex, the kinase and the interactor

Promotors: prof.dr. J.P.M. Geraedts, prof.dr. M.H. Hofker

Co-promotor: dr. M.J.W.M. Voncken

S.A. Weppler (2009, December 3^rd)

The regulation of protein synthesis by mTOR signaling: a potential target for cancer treatment?

Promotors: prof.dr. B.G. Wouters, prof.dr. P. Lambin

Co-promotors: dr. M.A.M. van Steensel, dr. G. Lammering

J.E. de Barque Hubert (2009, December 3^rd)

The realities of life for people with severe and profound intellectual disabilities and mental health problems

Promotors: prof.dr. L.M.G. Curfs, prof.dr. S. Hollins

H.W.F. van Eijndhoven (2009, December 11^th)

Mechanisms of Vasidilation in early pregnancy. Studies in instrumented conscious rats and isolated rat arteries

Promotors: prof.dr. J. de Haan, prof.dr. J.G.R. De Mey

Co-promotor: dr. L.L.H. Peeters

J. van Aalst (2009, December 18^th)

Embryological and surgical aspects of the tethered cord

Promotors: prof.dr. J.S.H. Vles, prof.dr. E.A.M. Beuls

2008

Baardwijk A.A.W. van (2008, May 29^th)

Radiotherapy in non-small cell lung cancer

Promotor: prof.dr. P. Lambin

Co-promotor: dr. D.K.M. de Ruysscher

Beucken A.M. van den (2008, September 11^th)

Translational control during hypoxia: Consequences for gene expression and hypoxia tolerance

Promotors: prof. dr. B.G. Wouters, prof.dr. P. Lambin

Co-promotor: dr. M. Koritzinsky

Bongaerts B.W.C. (2008, October 16^th)

Alcohol consumption as a risk factor for colorectal cancer: An epidemiological study on genetic susceptibility and molecular endpoint

Promotor: prof.dr. P.A. van den Brandt

Co-promotors: dr. M.P. Weijenberg, dr. A.F.P.M. de Goeij

Castermans K.E.R. (2008, February 1^st)

Relationship between angiogenesis and the immune response against solid tumours

Promotor: prof.dr. A.W. Griffioen

Eijsden R.G.E. van (2008, May 22^nd)

Microarray analysis of oxidative phosphorylation disorders

Promotor: prof.dr. J.P.M. Geraedts

Co-promotor: dr. H.J.M. Smeets

Essers B.A.B. (2008, June 5^th)

Surgical excision and Mohs micrographic surgery for basal cell carcinoma: An evaluation from different perspectives

Promotors: prof.dr. M.H. Prins, prof.dr. H.A.M. Neumann

Co-promotor: dr. C.D. Dirksen

Geomini P.M.A.J. (2008, December 19^th)

Pre- and peri-operative assessment of the adnexal mass

Promotors: prof.dr. J.L.H. Evers, prof.dr. B.W.J. Mol

Gestel I. van (2008, December 4^th)

Endometrial wave-like activity in assisted reproduction

Promotor: prof.dr. J.L.H. Evers

Co-promotors: dr. G. Hoogland, dr. M.M. IJland

Hillen F. (2008, February 21^st)

Tumour cell plasticity: vascularisation beyond angiogenesis

Promotor: prof. dr. A.W. Griffioen

Hoving M.A. (2008, May 23^rd)

Intrathecal baclofen therapy in children with intractable spastic cerebral palsy; A Dutch national study

Promotors: prof.dr. J.S.H. Vles, prof.dr. E.A.M. Beuls

Co-promotors: dr. E.P.M. van Raak, dr. G.H.J.J. Spincemaille

Jansen E.J.P. (2008, November 11^th)

Articular cartilage lesions; Advances in conservative and surgical interventions

Promotors: prof.dr. G.H.I.M. Walenkamp, prof.dr. S.K. Bulstra

Co-promotors: dr. R. Kuijer, dr. L.W. van Rhijn

Magagnin M.G.P. (2008, September 11^th)

Cellular adaption to hypoxia and reoxygenation through gene specific mRNA translation

Promotors: prof. dr. B.G. Wouters, prof.dr. P. Lambin

Co-promotor: dr. M. Koritzinsky

Pijls-Johannesma M.C.G. (2008, December 9^th)

Optimization of radiotherapy in Lung cancer treatment: balance between survival and quality of life

Promotor: prof.dr. P. Lambin

Co-promotors: dr. D.K.M. de Ruysscher, dr. L.J. Boersma

Seute T. (2008, February 1^st)

Neurologic complications in small cell lung cancer

Promotors: prof.dr. M. Limburg, prof.dr. M.H. Prins

Co-promotors: dr. A. Twijnstra, dr. G.P.M. ten Velde

Spruijt L. (2008, February 27^th)

Leber's Hereditary Optic Neuropathy: an interaction between two genomes?

Promotor: prof.dr. C.T.R.M. Stumpel - Schrander

Co-promotors: dr. H.J.M. Smeets, dr. C.E.M. de Die - Smulders

Tack F.B. (2008, June 6^th)

Post transcriptional gene silencing and peptide microarray as a way to perform drug target validation

Promotors: prof.dr. F.C.S. Ramaekers, prof.dr. M. Borgers

Co-promotor: dr. M. Janicot

Vissers Y.L.J. (2008, April 11^th)

Peri-operative arginine metabolism in cancer

Promotors: prof.dr. M.F. von Meyenfeldt, dr. N.E.P. Deutz

Co-promotors: prof. dr. C.H.C. Dejong, dr. Y.C. Luiking

Vliegen R.F.A. (2008, June 18^th)

Rectal Cancer Imaging; staging and restaging

Promotors: prof.dr. R.G.H. Beets-Tan, prof.dr. J.M.A. van Engelshoven

Co-promotor: dr. G.L. Beets

2007

Aardenburg R. (2007, December 6^th)

Low plasma volume in the pathophysiology of preeclampsia

Promotors: prof.dr. J. de Haan, prof.dr. P.W. de Leeuw

Co-promotors: dr. L.L.H. Peeters, dr. M.E. Spaanderdam

Bedaiwy M.A. (2007, December 19^th)

Ovarian tissue cryopreservation and transplantation: approaches and techniques

Promotor: prof.dr. J.L.H. Evers

Bertelli G. (2007, February 2^nd)

Tamoxifen and beyond: anti-estrogens and aromatase inhibitors in the hormonal therapy of breast cancer

Promotor: prof.dr. J. Wagstaff

Bosmans G.H.K. (2007, December 20^th)

CT/PET imaging of lung cancer patients for radiotherapy

Promotor: prof.dr. P. Lambin

Co-promotors: dr. D.K.M. de Ruysscher, dr. A.L.A.J. Dekker

Brandwijk R.J.M.G.E. (2007, September 20^th)

Targeted treatment of cancer using the angiogenesis inhibitor anginex

Promotor: prof.dr. A.W. Griffioen

Co-promotor: dr. V.L.J.L. Thijssen

Cignacco-Müller E.L.C. (2007, December 5^th)

Pain in neonates: a nursing perspective

Promotors: prof.dr. J.P.H. Hamers, prof.dr. L.J.I. Zimmermann

Co-promotors: dr. R.A. van Lingen, dr. M. Nelle

Emans P.J. (2007, April 5^th)

Towards in situ chondrogenesis of periosteum; a novel approach for cartilage repair?

Promotors: prof.dr. R.G.T. Geesink, prof.dr. S.K. Bulstra

Co-promotors: dr. R. Kuijer, dr. L.W. van Rhijn

Jacobs L.J.A.M. (2007, December 13^th)

The transmission and segregation of mitochondrial DNA mutations

Promotor: prof.dr. J.P.M. Geraedts

Co-promotors: dr. H.J.M. Smeets, dr. I.F.M. de Coo

Jong N. de (2007, May 30^th)

Fatigue in breast cancer patients receiving adjuvant chemotherapy

Promotors: prof.dr. H.C. Schouten, prof.dr. H. Abu Saad - Huijer

Co-promotor: dr. A.M. Courtens

Jonkers, Y.M.H. (2007, June 14^th)

Molecular alterations during insulinoma tumorigenesis

Promotor: prof.dr. F.C.S. Ramaekers

Co-promotor: dr. E.-J.M. Speel

Kramer B.W.W. (2007, October 10^th)

The ambiguous effects of exposure to antenatal inflammation in the fetal lung

Promotors: prof.dr. L.J.I. Zimmermann, prof.dr. A.H. Jobe

Kuijpers D.I.M. (2007, March 16^th)

Shedding new light on the treatment of basal cell carcinoma

Promotors: prof.dr. H.A.M. Neumann, prof.dr. P.M. Steijlen

Co-promotor: dr. M.R.T.M. Thissen

Molkenboer J.F.M. (2007, December 11^th)

Aspects of term breech deliveries in current medical practice

Promotor: prof.dr. J.G. Nijhuis

Co-promotors: dr. F.J.M.E. Roumen, dr. L.J.M. Smits

Montfoort A.P.A. van (2007, June 13^th)

Prevention of twin pregnancies in IVF by single embryo transfer

Promotors: prof.dr. J.L.H. Evers, prof.dr. J.P.M. Geraedts

Co-promotor: dr. J.C.M. Dumoulin

Neer P.A.F.A. van (2007, May 4^th)

The role of incompetent perforating veins in varicose veins

Promotor: prof.dr. H.A.M. Neumann

Co-promotor: dr. J.C.J.M. Veraart

Pullen J. (2007, April 26^th)

Pharmacokinetics and dosing of antibiotics in neonates

Promotors: prof.dr. L.J.I. Zimmermann, prof.dr. C. Neef

Co-promotors: dr. L.M.L. Stolk, dr. P.L.J. Degrauwe

Tuffrey-Wijne I.M.M. (2007, November 2^nd)

Palliative care for people with intellectual disabilities

Promotors: prof.dr. L.M.G. Curfs, prof.dr. S. Hollins

Verfaille C.J. (2007, April 27^th)

Retinoic acid metabolism blocking agents (RAMBAs) in hyperkeratotic disorders

Promotors: prof.dr. M. Borgers, prof.dr. F.C.S. Ramaekers, prof.dr. P.M. Steijlen

Co-promotors: dr. M.A.M. van Steensel

2006

Beijnum J.R. van (2006, April 27^th)

Gene expression profiling of tumour angiogenesis

Promotor: prof.dr. A.W. Griffioen

Besien K. van (2006, April 13^th)

Indolent lymphoma - diagnostic, prognostic and therapeutic paradoxes

Promotor: prof.dr. H.C. Schouten

Cloosen S. (2006, November 23^rd)

Dendritic cells, Mucin-1 and cancer vaccines

Promotor: prof.dr. H.C. Schouten

Co-promotors: dr. G.M.J. Bos, dr. W.T.V. Germeraad

Dijk B.A.C. van (2006, February 17^th)

Renal cell carcinoma: Risk factors & von Hippel-Lindau gene mutations

Promotors: prof.dr. P.A. van den Brandt, prof.dr. J.A. Schalken

Co-promotor: dr. L.J. Schouten

Dirkx A.E.M. (2006, March 23^rd)

Interplay between tumour angiogenesis and the immune system: Towards a new cancer therapy

Promotors: prof.dr. J. Wagstaff, prof.dr. A.W. Griffioen

Co-promotor: dr. M.G.A. Oude Egbrink

Gijsen A.P. (2006, March 10^th)

Chlamydia trachomatis antibody testing in screening for tubal factor sub-fertility

Promotors: prof.dr. J.L.H. Evers, prof.dr. C.A.M.V.A. Bruggeman

Co-promotor: prof.dr. J.A. Land

Heijden O.W.H. van der (2006, November 9^th)

Vascular remodelling of the uterine artery during pregnancy; studies in mice

Promotors: prof.dr. J. de Haan, prof.dr. J.G.R. De Mey

Co-promotors: dr. G.J.J.M. van Eys, dr. L.L.H. Peeters

Hellebrekers D.M.E.I. (2006, November 2^nd)

Epigenetic regulation of tumour angiogenesis

Promotor: prof.dr. A.W. Griffioen

Co-promotor: dr. M. van Engeland

Hove D.L.A. van den (2006, April 27^th)

Prenatal stress and adult psychopathology

Promotors: prof.dr. H.P.J. Steinbusch, prof.dr. C.E. Blanco

Co-promotors: dr. J.H.H.J. Prickaerts, dr. A. Scheepens

Ostertag J.U. (2006, June 15^th)

Laser resurfacing in the treatment of potential malignant skin diseases: Just optical improvement?

Promotors: prof.dr. H.A.M. Neumann, prof.dr. P.M. Steijlen

Co-promotor: dr. G.A.M. Krekels

Panis B. (2006, November 9^th)

Classical galactosemia: new insights

Promotors: prof.dr. J.P.M. Geraedts, prof.dr. L.J.I. Zimmermann

Co-promotor: dr. M.E. Rubio-Gozalbo

Quaedackers J.J.S.L.T. (2006, April 20^th)

Systemic complications in the preterm fetus after asphyxia

Promotors: prof.dr. J. de Haan, prof.dr. E. Heineman

Co-promotors: dr. L. Bennet, dr. A.J. Gunn

Quaedvlieg P.J.F. (2006, September 29^th)

From actinic keratosis to squamous cell carcinoma: A guideline for the clinician

Promotor: prof.dr. P.M. Steijlen

Co-promotors: dr. G.A.M. Krekels, dr. M.R.T.M. Thissen

Roelfsema V. (2006, April 20^th)

Recovery from severe perinatal hypoxia-ischaemia: Studies of pathophysiology and treatment in the fetal sheep

Promotors: prof.dr. J. de Haan, prof.dr. E. Heineman

Co-promotors: dr. L. Bennet, dr. A.J. Gunn

Torralba A.L.C. (2006, December 13^th)

Pulmonary circulation: Vasoactive factors, signalling pathways and therapeutic targets

Promotors: prof.dr. C.E. Blanco, prof.dr. Vizcaino Perez

Co-promotor: dr. E. Villamor

Vanclée A. (2006, November 23^rd)

A new model of haploidentical stem cell transplantation as a cure for malignancies in mice

Promotor: prof.dr. H.C. Schouten

Co-promotor: dr. G.M.J. Bos

Wever B. de (2006, February 3^rd)

Reconstituted human epidermal, corneal and oral epithelial tissue models

Promotors: prof.dr. F.C.S. Ramaekers, prof.dr. M. Borgers

2005

Baeten C.I.M. (2005, December 22^nd)

Angiogenesis and leukocyte infiltration in malignant carcinomas

Promotor: prof.dr. H.F.P. Hillen

Bosch A.M. (2005, September 21^st)

Diagnostic procedures in breast cancer

Promotor: prof.dr. M.F. von Meyenfeldt

Co-promotor: dr. G.L. Beets

Gyselaers W.J.A. (2005, December 6^th)

Screening for fetal trisomy 21 in North-Belgium

Promotor: prof.dr. J.G. Nijhuis

Co-promotors: prof.dr. I. Witters, prof.dr. W.U. Ombelet

Luchtenborg M. (2005, July 1^st)

A molecular epidemiologic study on colorectal cancer: meat, fat, smoking and genetic alterations

Promotors: prof.dr. P.A. van den Brandt, prof.dr. P. van ’t Veer

Co-promotors: dr. M. Weijenberg, dr. A.F.P.M. de Goeij

Lutgens L.C.H.W. (2005, December 2^nd)

Citrulline; a serological parameter for monitoring epithelial small bowel cancer treatment induced injury

Promotors: prof.dr. P. Lambin, prof.dr. M.F. von Meyenfeldt

Co-promotors: dr. N.E.P. Deutz, dr. B.G. prof. dr. B.G. Wouters

Moog U. (2005, November 11^th)

On the etiology of mental retardation: The clinical genetic approach

Promotors: prof.dr. J.P. Fryns, prof.dr. J.P.M. Geraedts, prof.dr. C.T.R.M. Schrander-Stumpel

Pijnenborg J.M.A. (2005, December 2^nd)

The predictive value of molecular markers for recurrent endometrial carcinoma

Promotor: prof.dr. J. de Haan

Co-promotor: dr. P.G. Groothuis

Poortmans P.M.P. (2005, June 10^th)

Quality assurance in clinical trials in breast cancer

Promotors: prof.dr. P. Lambin, prof.dr. W. van den Bogaart

Co-promotor: dr.ir. J.B. Davis

Smeets E.E.J. (2005, June 1^st)

Rett Syndrome 1954-2004

Promotors: prof.dr. C.T.R.M. Schrander-Stumpel, prof.dr. J.P. Fryns

Steensel M.A.M. van (2005, March 9^th)

Clinical and molecular genetic studies in hereditary hair loss

Promotors: prof.dr. P.M. Steijlen, prof.dr. P.C.M. van de Kerkhof

Co-promotor: dr. M. van Geel

Vervest A.M.J.S. (2005, January 26^th)

Zweymüller cementless total hip arthroplasty with two designs of titanium rectangular stem and a titanium threaded cup: A clinical, radiological and DEXA study

Promotor: prof.dr. R.G.T. Geesink

Wouw A. van den (2005, July 1^st)

Unknown Primary Tumour

Promotor: prof.dr. H.F.P. Hillen

Co-promotors: dr. R.L.H. Jansen, dr. E.-J.M. Speel

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