- The Scientific Director: Prof. Dr. Frans Ramaekers
- Leaders of the Division Developmental Biology: Prof. Christine E.M. de Die-Smulders and Prof. Dr. Luc Zimmerman
- Leaders of the Division Oncology: Prof. Dr. Philippe Lambin and Prof. Dr. Manon van Engeland
The Board is responsible for decision making on all activities within the Research School, herein assisted by the Managing Director. The Institute Board meets on the first Thursday of each month.
Managing Director a.i.: Judith Doomen.
The daily management is the responsibilty of the Scientific Director and the Managing Director, supported in their tasks by the Secretary.
Secretary's Office: Brigitte Custers & Tamara van de Laar
Besides these monthly Board meetings the Project Leaders participating within the Research school meets once a month.
The total number of scientific and support staff participation within GROW approximates 320, including 120 PhD students.
Prof. F.C.S. Ramaekers, PhD
Molecular Cell Biologist
Department of Molecular Cell Biology
Phone: +31 (0)43 38 813 51
Fax: +31 (0)43 38 841 51
Professor Frans C.S. Ramaekers (1952) was trained as a chemist at the University of Nijmegen, specialized in Biochemistry at the Universityof Nijmegen and Pharmaco-chemistry at Organon, Oss, and graduated in 1977. He received his PhD degree in 1981 at the Universityof Nijmegen on basis of a thesis on the role of the cytoskeleton in cell differentiation.
From 1981 to 1990 he was appointed as associate professor at the Department of Pathology of the University Hospital in Nijmegen, where studies on the application of cytoskeletal elements in cancer diagnosis were performed. In 1989 he received the Bristol-Meyers Oncology Award for this work.
In June 1989 he was appointed professor of Molecular Cell Biology at the Maastricht University and became chairman of the Department of Molecular Cell Biology & Genetics.
He has been president of the European Cytoskeleton Forum, chairman of the Dutch Society for Cell Biology, member of the board of the Dutch Society for Oncology, of the Federation of Medical Scientific Societies and of the Society of Experimental Biology (UK), and is member of the editorial board of several international journals, including Cytometry, Applied Immuno-histochemistry, Molecular Biology Reports, and Progress in Histochemistry and Cytochemistry.
He has published over 450 peer-reviewed papers and over 50 book contributions and national papers. He is scientific director of MUbio Products B.V.
As of March 2010 he has been appointed as scientific director of GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, for a period of six years.
Prof. M. van Engeland, PhD
Department of Pathology
Phone: +31 (0)43 387 46 22
Fax: +31 (0)43 387 66 13
Professor Manon van Engeland studied Biological Health Sciences at Maastricht University, graduated in 1995 and obtained a PhD in Cell Biology 1999 at Maastricht University.
In 2000, she moved to the US to perform a postdoctoral fellowship in the laboratory of Prof. James G. Herman and Stephen B. Baylin at the Johns Hopkins University School of Medicine (Baltimore, USA).
During this fellowship she developed a strong interest in translational cancer epigenetics, particularly in the identification of promoter CpG island hypermethylated tumor suppressor genes.
Upon her return to Maastricht University in 2001, she started her research line on translational cancer epigenetics and founded the Cancer Pathology Laboratory at the dept. of Pathology at Maastricht University Medical Center, which she is currently heading.
She was appointed Assistant Professor and Associate Professor in 2003 and 2007 resp. Since 2009, she is division leader Oncology at GROW-the School for Oncology and Developmental Biology at Maastricht University Medical Center.
In March 2011 she was appointed as extraordinary professor pathobiology of cancer, specifically the role of epigenetics. She has obtained grants from the Dutch Cancer Society, ZONMW, SenterNovem and CTMM. For the CTMM DeCoDe project she is the deputy coordinator.
She has supervised 7 PhD projects, co-authored over 60 scientific papers in peer-reviewed journals and is co-inventor of three patents. Prof. van Engeland's laboratory is focussing on translational cancer epigenetics aiming to identify promoter methylation markers for early detection and prediction of prognosis and response to therapy in colorectal-, breast-, kidney and skin cancer.
Prof. P. Lambin, MD, PhD
Department of Radiation Oncology
Phone: +31 (0)88 44 55 754
Fax: +31 (0)88 44 55 776
Professor Philippe Lambin, MD, PhD was born in 1961, became doctor of medicine in 1986 and specialized in Radiation Oncology in 1991 at the Catholic University of Louvain (UCL) in Belgium. In 1995 he received his PhD degree in Paris on the Radiation Sensitivity of human tumour cells. From 1993 to 1999 he was appointed, as Radiation Oncologist in the departement of the University Hospital Gasthuisberg in Leuven (KUL). Since 2000, he has held the position as seated Professor in Radiation Oncology at the University of Maastricht, Head of the department for Radiation Oncology of the University Hospital of Maastricht, Medical Director of the MAASTRO CLINIC, Division leader of the Research institute GROW and more recently he has also been appointed as Professor of Functional Imaging in Radiation Oncology at the Technical University of Eindhoven. He has been visiting professor at the university of Leuven, Philadelphia and Toronto.
Over the past thirteen years, he has received many awards which includes the 1991 Fullbright-Haze Award for research in the US, the 1993 ESTRO Varian Award, the 1995 Young Scientist Award of the Radiation Research Society (RRS), the 1996 Fellowship of Flemish Funds for Scientific Research, two prizes once in 1996 and again in 2002 from the Royal Belgian Academy of Medicine and the Breur Award from the European Society of Radiation Oncology (ECOO meeting, Berlin, 2009).
Complimenting these activities on both a European and International basis, he is a member of numerous scientific societies and a key contributor at various (inter)national scientific committees (e.g. ESTRO, CKTO, KWF, EU). Continuous involvement as a principal investigator in his specialized area has lead him to head more than 32 research grants and publish more than 204 peer reviewed papers with over 500 conferences contributions. Besides projects supported by cancer foundations and EU, he had/has many collaborations with pharma and imaging industry. He supervised more then 24 PhD projects, is author and co- and is (co)inventor of 11 patents (Four officially granted, 7 submitted not yet officially filed).
His main areas of interest are directed towards translational research in Radiation Biology with a specific focus on tumor hypoxia, functional imaging (CT-PET) and lung cancer. He has a recent interest in the develoment of a “treatment decision support system” based on multiparametric databases containing clinical, imaging, biological and therapeutic information.
Prof. L.J.I. Zimmermann, MD, PhD
Department of Pediatrics
Phone: +31 (0)43 38 77 250
Fax: +31 (0)43 38 75 246
Professor Luc J.I. Zimmermann was born in 1959 in Belgium. He graduated as MD in 1984 at the Catholic University of Leuven, Belgium and did his residency in Pediatrics at the same university, in the University Hospital Gasthuisberg Leuven, Belgium (1984-1989).
He trained as a Fellow in Neonatology at the Hospital for Sick Children and the University of Toronto Perinatal Fellowship Program in Toronto, Canada from 1989 to 1992. From 1992 to 2003 he was a staff Neonatologist at the Erasmus Medical Center – Sophia in Rotterdam, where he was Chief of the Division of Neonatology a.i. from 2000 to 2003.
His PhD thesis (in 1995) was titled "Regulation of CTP:phosphocholine cytidylyltransferase in fetal type II cells". In 2003 he became a staff neonatologist at the Academic Hospital Maastricht, in 2004 Professor in Pediatrics and in 2005 Chief of the Division of Neonatology.
In 2006 he became Chairman of the Department of Pediatrics and Director of the Residency Program in Pediatrics. In July 2006 he took over as Division leader in GROW from Carlos E. Blanco.