The research in the division
Developmental Biology is devoted to genetics and reproduction on the one hand
and pregnancy and child on the other. It is a mixture of fundamental studies
and applied research. Reproductive
medicine and genetics have had a tremendous development during the last years.
This has brought forward many new options for diagnosis and treatment before, during
and after pregnancy. It is obvious that these developments lead to new research
aims which in turn change the clinical approaches that are offered. However,
the effectiveness, safety and risks of the procedures, which are introduced in
the clinical practise, have not always been studied properly. In this division
reproductive medicine, foetal and perinatal medicine go hand in hand, which
gives a lot of new opportunities with respect to longitudinal approaches and
the study of long term consequences.
Many of these aspects are
studied in each of the following research lines, although the balance is
variable. Quite a number of research questions that are addressed in the
Division Developmental Biology are linked to studies that are done within the
Division Oncology. For example similar methods are used in the fields of
genetics, epigenetics and
genomics or similar problems are studied like angiogenesis, apoptosis and
hypoxia.
Research lines and their leaders:
1 Fertility
(Dr. J.A. Land and Prof.dr. J. Evers)
2 Early Embryonic Development (Dr. J.
Dumoulin and Dr. H. van Straaten)
3 Epigenetics and Gene Expression (Dr. JW.
Voncken)
4 Clinical Genetics (Prof. C.
Schrander-Stumpel and Dr. B. Smeets)
5 Genital
Tract (Dr. P. Groothuis and Dr. G. Dunselman)
6 Maternal Physiology (Dr. L. Peeters)
7 Perinatal Stress (Prof.dr. C. Blanco en
Prof.dr. L. Zimmermann)
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